Failure of mitochondrial quality control causes heart disease

Mutations in the gene that encodes a protein called adenine nucleotide translocator (ANT) cause a variety of conditions, such as heart disease and weakness of the eye muscles, but the underlying mechanism of how these mutations trigger disease has been unclear. Now, researchers at Penn Medicine discovered that ANT is critical for a quality control process called mitophagy—which helps to ensure the integrity of the mitochondria network by removing damaged mitochondria—and found that mutations that lead to a defective quality control system ultimately cause heart disease.

From http://besthealthnews.com/2019/10/failure-of-mitochondrial-quality-control-causes-heart-disease/?utm_source=rss&utm_medium=rss&utm_campaign=failure-of-mitochondrial-quality-control-causes-heart-disease

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from https://aubreyflores.blogspot.com/2019/10/failure-of-mitochondrial-quality.html

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From https://tommysmith1.blogspot.com/2019/10/failure-of-mitochondrial-quality.html

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https://tommysmith1.wordpress.com/2019/10/17/failure-of-mitochondrial-quality-control-causes-heart-disease/